Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17266 |
Xipamide
希伯胺,Diurexan,Aquaphor |
Others | Others |
Xipamide (Diurexan) 是一种磺胺类利尿剂,具有抗高血压特性。Xipamide 可选择性地抑制阴离子交换器。 | |||
T11528 |
H100
|
Others | Others |
H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger. | |||
T40926 |
Beta-D-Glucopyranosyl nitromethane
|
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Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane, functioning as a salt of a highly basic anion exchanger in the OH cycle. | |||
T20694 |
DIDS
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DIDS, an anion exchange inhibitor, acts by blocking reversibly and later irreversibly, exchangers such as chloride-bicarbonate exchanger. It is also a RAD51 inhibitor. | |||
T81539 | PAT1inh-B01 | ||
PAT1inh-B01为选择性SLC26A6抑制剂,抑制PAT1(Cl-/HCO3-交换器)介导的阴离子交换(IC50: 350 nM),并阻断小肠液体吸收,适用于小肠分泌不足相关疾病研究。 | |||
T74815 | SLC26A3-IN-2 | ||
SLC26A3-IN-2 是一种口服有效的阴离子交换蛋白 SLC26A3的抑制剂 (IC50=360 nM)。SLC26A3 属于溶质载体 (SLC) 蛋白,属于 SLC26 家族。SLC26 家族对氯化物、碳酸氢盐、硫酸盐和草酸盐具有广泛的阴离子特异性。SLC26A3 在腺瘤 (DRA) 中下调,参与氯化物和草酸盐的肠道吸收。SLC26A3 功能突变的丧失与氯离子丢失性腹泻有关。 |